BDBM50388602 FURAMIDINE

SMILES NC(=N)c1ccc(cc1)-c1ccc(o1)-c1ccc(cc1)C(N)=N

InChI Key InChIKey=ZJHZBDRZEZEDGB-UHFFFAOYSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50388602   

TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch Of The Russian Academy Of Science

Curated by ChEMBL
LigandPNGBDBM50388602(FURAMIDINE)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of recombinant human TDP1 measured by real-time oligonucleotide biosensor assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch Of The Russian Academy Of Science

Curated by ChEMBL
LigandPNGBDBM50388602(FURAMIDINE)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of human recombinant Tdp1 assessed as conversion of 14-mer 5'-32P-labeled 3'-phosphotyrosyl DNA substrate N14Y to 14-mer 5'-32P-labeled 3'...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch Of The Russian Academy Of Science

Curated by ChEMBL
LigandPNGBDBM50388602(FURAMIDINE)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of Tdp1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch Of The Russian Academy Of Science

Curated by ChEMBL
LigandPNGBDBM50388602(FURAMIDINE)
Affinity DataIC50:  1.23E+3nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch Of The Russian Academy Of Science

Curated by ChEMBL
LigandPNGBDBM50388602(FURAMIDINE)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch Of The Russian Academy Of Science

Curated by ChEMBL
LigandPNGBDBM50388602(FURAMIDINE)
Affinity DataIC50:  1.24E+3nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed